Xian Wu Selected Research

nobiletin

4/2020	Synergistic anticancer effects of curcumin and 3',4'-didemethylnobiletin in combination on colon cancer cells.
11/2019	Inhibitory effects of nobiletin and its major metabolites on lung tumorigenesis.
1/2018	A metabolite of nobiletin, 4'-demethylnobiletin and atorvastatin synergistically inhibits human colon cancer cell growth by inducing G0/G1 cell cycle arrest and apoptosis.
1/2017	Nobiletin and its colonic metabolites suppress colitis-associated colon carcinogenesis by down-regulating iNOS, inducing antioxidative enzymes and arresting cell cycle progression.
1/2017	Synergistic chemopreventive effects of nobiletin and atorvastatin on colon carcinogenesis.
12/2015	Inhibitory Effects of 4'-Demethylnobiletin, a Metabolite of Nobiletin, on 12-O-Tetradecanoylphorbol-13-acetate (TPA)-Induced Inflammation in Mouse Ears.
12/2015	Anti-inflammatory effects of 4'-demethylnobiletin, a major metabolite of nobiletin.
12/2015	Chemopreventive effects of nobiletin and its colonic metabolites on colon carcinogenesis.

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Xian Wu Research Topics

Disease

39	Neoplasms (Cancer) 05/2022 - 10/2011
16	Inflammation (Inflammations) 01/2022 - 12/2015
13	Carcinogenesis 12/2021 - 12/2015
10	Colonic Neoplasms (Colon Cancer) 06/2020 - 12/2015
9	Infections 01/2022 - 12/2015
8	Cognitive Dysfunction 10/2022 - 10/2018
8	Breast Neoplasms (Breast Cancer) 01/2021 - 01/2018
7	COVID-19 01/2021 - 10/2020
6	Alzheimer Disease (Alzheimer's Disease) 10/2022 - 01/2018
6	Neuroinflammatory Diseases 08/2022 - 10/2018
6	Colitis 06/2020 - 12/2015
5	Parkinson Disease (Parkinson's Disease) 01/2022 - 01/2018
4	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 12/2017
3	Chronic Obstructive Pulmonary Disease (COPD) 03/2022 - 04/2016
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 01/2018
3	Colorectal Neoplasms (Colorectal Cancer) 12/2021 - 08/2017
3	Glioma (Gliomas) 01/2021 - 05/2017
3	Critical Illness (Critically Ill) 12/2020 - 10/2020
3	Neoplasm Metastasis (Metastasis) 10/2020 - 08/2018
3	Heart Failure 06/2020 - 04/2016
3	Hypoxia (Hypoxemia) 06/2020 - 12/2017
3	Substance Withdrawal Syndrome (Withdrawal Symptoms) 02/2016 - 10/2015
2	Rectal Neoplasms (Rectal Cancer) 05/2022 - 01/2022
2	Type 2 Diabetes Mellitus (MODY) 01/2022 - 03/2019
2	Hyperglycemia 02/2021 - 01/2020
2	Intracranial Hypertension 01/2021 - 01/2020
2	Liver Cirrhosis (Hepatic Cirrhosis) 11/2020 - 08/2019
2	Stomach Neoplasms (Stomach Cancer) 01/2020 - 11/2019
2	Atrial Fibrillation 01/2020 - 01/2019
2	Thrombosis (Thrombus) 01/2020 - 01/2018
2	Neuroblastoma 11/2019 - 10/2017
2	Pre-Eclampsia (Preeclampsia) 07/2019 - 10/2018
2	Bone Resorption 03/2019 - 06/2013
2	Osteoporosis 01/2019 - 06/2013
2	Disease Progression 01/2018 - 01/2017
2	HIV Infections (HIV Infection) 01/2018 - 01/2017
2	Lung Neoplasms (Lung Cancer) 03/2017 - 06/2016

Drug/Important Bio-Agent (IBA)

21	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2002
12	CytokinesIBA 01/2022 - 01/2013
8	LipopolysaccharidesIBA 08/2022 - 12/2015
8	Pharmaceutical PreparationsIBA 12/2021 - 11/2013
8	Biomarkers (Surrogate Marker)IBA 01/2021 - 06/2013
8	AzoxymethaneIBA 06/2020 - 12/2015
8	nobiletinIBA 04/2020 - 12/2015
6	CurcuminIBA 12/2021 - 08/2017
5	MicroRNAs (MicroRNA)IBA 01/2021 - 02/2015
4	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2021
4	Immunoglobulin G (IgG)IBA 01/2021 - 10/2020
4	AntibodiesIBA 01/2021 - 12/2020
4	FlavonoidsIBA 06/2020 - 06/2016
4	Dextran SulfateIBA 06/2020 - 12/2015
3	Peptides (Polypeptides)IBA 10/2022 - 03/2019
3	O-1602 compoundIBA 10/2022 - 01/2022
3	Streptozocin (Streptozotocin)FDA Link 08/2022 - 01/2022
3	Amyloid beta-PeptidesIBA 08/2022 - 10/2018
3	6alpha-ethyl-23(S)-methylcholic acidIBA 01/2022 - 10/2018
3	Neuroprotective AgentsIBA 01/2022 - 10/2018
3	Messenger RNA (mRNA)IBA 05/2021 - 04/2002
3	TeaIBA 05/2021 - 01/2020
3	Immunoglobulin M (IgM)IBA 01/2021 - 12/2020
3	PolyphenolsIBA 06/2020 - 03/2018
3	5-demethylnobiletinIBA 06/2020 - 06/2016
3	LipidsIBA 01/2020 - 01/2017
3	SynucleinsIBA 01/2020 - 01/2018
3	CollagenIBA 08/2019 - 03/2018
3	Cisplatin (Platino)FDA LinkGeneric 12/2017 - 02/2015
3	DNA (Deoxyribonucleic Acid)IBA 12/2017 - 04/2002
3	Serotonin (5 Hydroxytryptamine)IBA 02/2016 - 10/2015
3	Naloxone (Narcan)FDA LinkGeneric 02/2016 - 10/2015
2	Amyloid (Amyloid Fibrils)IBA 10/2022 - 01/2018
2	ORALIT (ORS)IBA 05/2022 - 01/2015
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2022 - 12/2021
2	ResveratrolIBA 01/2022 - 01/2016
2	Bile Acids and Salts (Bile Acids)IBA 01/2022 - 01/2019
2	ProteomeIBA 01/2021 - 12/2020
2	EnzymesIBA 12/2020 - 01/2017
2	Biological ProductsIBA 04/2020 - 04/2002
2	p38 Mitogen-Activated Protein KinasesIBA 01/2020 - 01/2018
2	Phosphotransferases (Kinase)IBA 01/2020 - 05/2017
2	Serine (L-Serine)FDA Link 01/2020 - 01/2018
2	4- (N- methyl- N- nitrosamino)- 1- (3- pyridyl)- 1- butanoneIBA 11/2019 - 03/2017
2	Dextrans (Dextran)FDA Link 10/2019 - 01/2019
2	sodium sulfate (sodium bisulfate)FDA LinkGeneric 10/2019 - 01/2019
2	ursodoxicoltaurineIBA 07/2019 - 01/2013
2	salicylsalicylic acid (salsalate)IBA 01/2019 - 08/2017
2	Toll-Like Receptor 4IBA 10/2018 - 12/2015
2	Hormones (Hormone)IBA 10/2018 - 01/2018
2	Oxygen (Dioxygen)IBA 08/2018 - 01/2018
2	4'-demethylnobiletinIBA 01/2018 - 12/2015
2	Atorvastatin (Lipitor)FDA Link 01/2018 - 01/2017

Therapy/Procedure

21	Therapeutics 12/2021 - 10/2011
5	Radiotherapy 05/2022 - 01/2018
4	Drug Therapy (Chemotherapy) 01/2020 - 08/2016
4	Oral Administration 11/2019 - 12/2015
2	Aftercare (After-Treatment) 10/2020 - 01/2018
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 04/2020 - 01/2020
2	Adjuvant Chemotherapy 01/2020 - 10/2018
2	Secondary Prevention 11/2019 - 10/2017
2	Adjuvant Radiotherapy 10/2018 - 01/2018
2	Chemoprevention 01/2017 - 06/2016